Accurate dosing of syrups may be difficult as it requires precise volume measurement in the field. A new dispersible formulation of AL, specifically designed for children, has proved in clinical trials to be as safe and effective as the regular tablet formulation [ 31 ].
Educating healthcare workers and patients about the prevention and treatment of malaria is another challenge in the management of the disease. One of the greatest difficulties in reducing the toll of malaria is reaching remote communities with poor transport systems, and achieving timely reordering to maintain supplies of ACT.
The procurement of anti-malarial medicines through public health services increased sharply between and , but access to treatment, especially ACT, was inadequate in all countries surveyed in [ 1 ]. Novartis is helping to address these challenges by hosting a series of biannual workshops in Africa, at which national malaria control programme NMCP managers can share information regarding best practice in their countries, including topics such as community awareness, healthcare worker training, stock management and distribution, and health impact measurement.
Participants can also share expertise on how to forecast demand for AL, as well as discussing ordering and distribution systems, and routes for financing and procurement. Malaria continues to be a significant public health issue and a major hindrance to economic growth. Sustained control and management of malaria presents significant challenges.
Effective interventions are available; these include widespread implementation of effective vector control measures such as LLINs and IRS, and prompt and effective treatment with ACT following accurate diagnosis. Reducing malaria transmission by reducing gametocyte carriage with effective drugs can be an important factor in highly endemic areas. Some endemic countries are forging a path in malaria control and prevention using combined interventions and have achieved significant reductions in malaria burden.
However, factors such as patient access to effective treatments and preventative measures, availability of training programmes and educational materials, and development and spread of resistance to certain anti-malarials are hindering progress. Addressing the continuing challenges presented by malaria in the years ahead will require responsive strategies such as innovative vector control methods, widespread implementation of biological diagnosis prior to treatment with effective anti-malarials, and close monitoring of local malaria epidemiology to identify areas of resurgence.
Tight control of the regulatory environment to ensure provision of high-quality drugs and appropriate dosing advice will be vital to promoting compliance and preserving effectiveness of ACT. Roll Back Malaria.
Key malaria facts. Roll Back Malaria Partnership. Africa Malaria Report - Chapter 2: Insecticide-treated nets. Chapter 6: Resource mobilization and financing. Malar J. Fillinger U, Lindsay SW: Suppression of exposure to malaria vectors by an order of magnitude using microbial larvicides in rural Kenya.
Trop Med Int Health. Trends Parasitol. Article PubMed Google Scholar. Vestergaard LS, Ringwald PL: Responding to the challenge of antimalarial drug resistance by routine monitoring to update national malaria treatment policies. Am J Trop Med Hyg. PubMed Google Scholar.
The use of antimalarials. Lancet Infect Dis. White NJ: Antimalarial drug resistance. J Clin Invest. White NJ: Intermittent presumptive treatment for malaria. PLoS Med. White NJ: How antimalarial drug resistance affects post-treatment prophylaxis. N Engl J Med. Clin Pharmacokinet. Google Scholar. Article Google Scholar. Download references. Publication of the supplement has been sponsored by Novartis Pharma AG.
You can also search for this author in PubMed Google Scholar. Correspondence to Gilbert Kokwaro. The author would like to acknowledge that Novartis Pharma AG sponsored this supplement. However, the author does not work for, or represent in any way, Novartis Pharma AG. This article is published under license to BioMed Central Ltd. Reprints and Permissions. Kokwaro, G.
Ongoing challenges in the management of malaria. Malar J 8, S2 Download citation. Published : 12 October Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article.
Provided by the Springer Nature SharedIt content-sharing initiative. Skip to main content. Search all BMC articles Search. It is just so important — looking forward — to keep these obstacles in mind and be realistic as to what can be achieved in what time frame. The leaders present at the Global Malaria Forum did exactly this.
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